Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880812 | 0.85 | — | — | |
| SCHEMBL769669 | 0.85 | DYRK1A (0.46) | DYRK1ATLR8ALDH1A1MAPTLMNA | |
| SCHEMBL1343169 | 0.79 | DYRK1A (0.42) | DYRK1ATLR8ALDH1A1MAPTLMNA | |
| SCHEMBL16953469 | 0.79 | DYRK1A (0.38) | DYRK1ATLR8ALDH1A1MAPTLMNA | |
| SCHEMBL2417697 | 0.75 | CYP3A4 (0.40) | ALDH1A1MAPTTSHRKDM4EMEN1 | |
| SCHEMBL16959168 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPTTSHRKDM4EMEN1 | |
| SCHEMBL28351566 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNATSHRKDM4E | |
| SCHEMBL22288144 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9329818 | 0.74 | L3MBTL1 (0.47) | DYRK1AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL22288139 | 0.73 | DYRK1A (0.31) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074241-A1 | INHIBITOR AGAINST INTERACTION BETWEEN PD-1 AND PD-L1, COMPRISING PHENYLACETYLENE DERIVATIVE | 정원혁 | 2019-04-18 | — | — | WO | disclosed |