Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22582347 | 0.78 | DRD2 (0.42) | DRD2DRD3CYP1A1KCNH2HDAC1 | |
| SCHEMBL17080578 | 0.78 | DRD2 (0.48) | DRD2DRD3CYP1A1KCNH2HDAC1 | |
| SCHEMBL20911963 | 0.77 | DRD2 (0.48) | DRD2DRD3KCNH2HDAC1RAB9A | |
| SCHEMBL17912986 | 0.73 | HDAC1 (0.69) | DRD2DRD3KCNH2HDAC1RAB9A | |
| SCHEMBL19297530 | 0.72 | RAB9A (0.45) | DRD2DRD3HDAC1RAB9A | |
| SCHEMBL20911965 | 0.71 | HDAC1 (0.45) | DRD2DRD3CYP1A1KCNH2HDAC1 | |
| SCHEMBL31662551 | 0.71 | DRD2 (0.48) | DRD2DRD3CYP1A1KCNH2HDAC1 | |
| SCHEMBL6752773 | 0.71 | LARS1 (0.56) | DRD2DRD3KCNH2HDAC1RAB9A | |
| SCHEMBL6751647 | 0.70 | LARS1 (0.58) | DRD2DRD3KCNH2HDAC1RAB9A | |
| SCHEMBL16915090 | 0.70 | HDAC1 (0.67) | DRD2DRD3HDAC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073253-A1 | MAP4K4 INHIBITORS | IMPERIAL INNOVATIONS LIMITED (GB) | 2019-04-18 | — | — | WO | disclosed |