Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11786773 | 0.98 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11350134 | 0.87 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14274485 | 0.87 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL21551486 | 0.86 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2091369 | 0.85 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2306741 | 0.85 | KMT2A (0.69) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11850690 | 0.84 | HPGD (0.70) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23797876 | 0.83 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5932331 | 0.83 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9312746 | 0.83 | KMT2A (1.00) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | claimed |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-07-07 | — | — | US | claimed |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-05-14 | — | — | US | claimed |
| EP-3630717-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | Council of Scientific and Industrial Research (IN) | 2020-04-08 | — | — | EP | claimed |
| WO-2018216036-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-11-29 | — | — | WO | claimed |
| WO-2009147216-A1 | NEW PYRIDINE DERIVATIVES AS LEPTIN RECEPTOR MODULATOR MIMETICS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| CN-110621678-B | Antitumor compounds | 法马马有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117865987-A | Antitumor compounds | 法马马有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-3630717-B1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | disclosed |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-07-07 | — | — | US | disclosed |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-05-14 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| WO-2009147216-A1 | NEW PYRIDINE DERIVATIVES AS LEPTIN RECEPTOR MODULATOR MIMETICS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-4138264-A | Silver halide emulsion containing two equivalent type coupler for use in photography | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | MEN1 4525/4885KMT2A 3324/4885SMN1; SMN2 3787/4885 |
| US-20200148631-A1 | A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES | TYR, DDC, ALK | MEN1 2035/4885KMT2A 257/4885SMN1; SMN2 4574/4885 |
| US-10703714-B2 | Process for the synthesis of aromatic carbamates | ALK, DDC, TYR | MEN1 1774/4885KMT2A 323/4885SMN1; SMN2 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.