SCHEMBL20915282

SCHEMBL20915282

BrCCc1c2ccccc2c(CCBr)c2c(Oc3c(Oc4ccccc4)ccc4c(CCBr)c5ccccc5c(CCBr)c34)c(Oc3ccccc3)ccc12

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
TTR P02766 2/20 0.32
DPP4 P27487 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
LTA4H P09960 1/20 0.31
TSHR P16473 1/20 0.31
SLC6A4 P31645 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20915392 0.86 KDM4E (0.41) HRH1KDM4EGLAMAPTKMT2A
SCHEMBL20915585 0.86 TTR (0.38) HRH1KDM4EGLAMAPTKMT2A
SCHEMBL20915653 0.83 RHEB (0.38) HRH1KDM4ETTRLTA4H
SCHEMBL20915526 0.83 TTR (0.34) HRH1KDM4EGLAMAPTKMT2A
SCHEMBL20915538 0.83 TTR (0.34) HRH1KDM4EGLAMAPTKMT2A
SCHEMBL20915399 0.83 LTA4H (0.40) KDM4EMAPTKMT2ALTA4HTSHR
SCHEMBL20915496 0.82 LTA4H (0.40) KDM4EMAPTLTA4HTSHR
SCHEMBL20915636 0.81 MCL1 (0.34) TTRLTA4H
SCHEMBL20915355 0.81 LTA4H (0.39) LTA4H
SCHEMBL20398445 0.81 LTA4H (0.39) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149103-B2 Photopolymerization sensitizer composition and photopolymerizable composition comprising the same KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-10-19 US disclosed
US-20190119426-A1 PHOTOPOLYMERIZATION SENSITIZER COMPOSITION AND PHOTOPOLYMERIZABLE COMPOSITION COMPRISING THE SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2019-04-25 US disclosed