⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257160 | 0.82 | — | — | |
| SCHEMBL9781323 | 0.82 | — | — | |
| SCHEMBL3156439 | 0.79 | — | — | |
| SCHEMBL44759 | 0.78 | — | — | |
| SCHEMBL4137037 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL3870846 | 0.75 | — | — | |
| SCHEMBL609764 | 0.72 | — | — | |
| SCHEMBL7519648 | 0.72 | — | — | |
| SCHEMBL502169 | 0.72 | — | — | |
| SCHEMBL7519518 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | claimed |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2022-06-23 | — | — | US | claimed |
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2019-04-25 | — | — | US | claimed |
| CN-109153655-A | For preventing or treating the novel N- acyl urea derivatives of cardiovascular disease and comprising its composition | 高丽大学校产学协力团 | 2019-01-04 | — | — | CN | claimed |
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | disclosed |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2022-06-23 | — | — | US | disclosed |
| US-11306073-B2 | N-acylurea derivative and composition comprising same for prevention or treatment of cardiovascular disease | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-04-19 | — | — | US | disclosed |
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2019-04-25 | — | — | US | disclosed |
| CN-109153655-A | For preventing or treating the novel N- acyl urea derivatives of cardiovascular disease and comprising its composition | 高丽大学校产学协力团 | 2019-01-04 | — | — | CN | disclosed |