SCHEMBL502169

SCHEMBL502169

NC(=O)C(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL1010986 0.79 ALDH1A1 (0.36)
SCHEMBL692716 0.75
SCHEMBL44759 0.75
SCHEMBL27588236 0.74
SCHEMBL25169780 0.72
SCHEMBL20915652 0.72
SCHEMBL836624 0.72
SCHEMBL25227005 0.72
SCHEMBL25241362 0.72
SCHEMBL3750293 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570668-B2 Single molecule compounds providing multi-target inhibition of BTK and other proteins and methods of use thereof SIGNALRX PHARMACEUTICALS, INC. (US) 2026-03-10 US claimed
US-20250093362-A1 HIGH-THROUGHPUT ENGINEERING OF MOLECULAR GLUES FRONTIER MEDICINES CORPORATION 2025-03-20 US claimed
US-20240002343-A1 COMPOUNDS HAVING INHIBITORY EFFECT ON MITOCHONDRIAL HYPERFISSION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-01-04 US claimed
EP-4252843-A1 COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS Kyushu University, National University Corporation (JP) 2023-10-04 EP claimed
US-20230220313-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS RNASSIST LTD. (GB) 2023-07-13 US claimed
EP-4133062-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS Rnassist Limited (GB) 2023-02-15 EP claimed
WO-2023015237-A1 HIGH-THROUGHPUT ENGINEERING OF MOLECULAR GLUES FRONTIER MEDICINES CORPORATION (US) 2023-02-09 WO claimed
WO-2022114187-A1 COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS 国立大学法人九州大学 2022-06-02 WO claimed
US-20260125421-A1 ANTIVIRAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2026-05-07 US disclosed
US-12570668-B2 Single molecule compounds providing multi-target inhibition of BTK and other proteins and methods of use thereof SIGNALRX PHARMACEUTICALS, INC. (US) 2026-03-10 US disclosed
WO-2025262036-A1 METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION RNASSIST LTD (GB) 2025-12-26 WO disclosed
EP-4532503-A1 HALOINDOLE MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2025-04-09 EP disclosed
US-20250093362-A1 HIGH-THROUGHPUT ENGINEERING OF MOLECULAR GLUES FRONTIER MEDICINES CORPORATION 2025-03-20 US disclosed
EP-4392424-A1 MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2024-07-03 EP disclosed
US-4670593-A Haloacetamidines and the herbicidal use thereof STAUFFER CHEMICAL CO. (US) 1987-06-02 US disclosed
US-4562009-A Halonitriles, their preparation and use to make halopyridines THE DOW CHEMICAL COMPANY (US) 1985-12-31 US disclosed
EP-0143465-A2 Novel halonitriles and their preparation THE DOW CHEMICAL COMPANY (US) 1985-06-05 EP disclosed
US-4361557-A 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor SCHERING CORPORATION (US) 1982-11-30 US disclosed
US-4311857-A 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor SCHERING CORPORATION (US) 1982-01-19 US disclosed
US-4235892-A AROMATIC ANTIBIOTICS Schering Corporation, Patent Dept. (US) 1980-11-25 US disclosed