Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438553 | 1.00 | OPRK1 (0.55) | OPRK1SIGMAR1MEN1KMT2ACA12 | |
| SCHEMBL20915921 | 1.00 | OPRK1 (0.55) | OPRK1SIGMAR1MEN1KMT2ACA12 | |
| SCHEMBL19438736 | 0.89 | SIGMAR1 (0.56) | SIGMAR1KMT2ACA12CA7CA9 | |
| SCHEMBL19438542 | 0.81 | SIGMAR1 (0.59) | SIGMAR1MEN1KMT2ACA12CA7 | |
| SCHEMBL19438777 | 0.81 | SIGMAR1 (0.59) | SIGMAR1CA12CA7CA9CA14 | |
| SCHEMBL19438607 | 0.81 | SIGMAR1 (0.61) | SIGMAR1CA12CA7CA9CA14 | |
| SCHEMBL4932073 | 0.80 | SIGMAR1 (0.62) | SIGMAR1CA12CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL19438468 | 0.80 | SIGMAR1 (0.58) | SIGMAR1CA12CA7CA9CA14 | |
| SCHEMBL8829830 | 0.80 | SIGMAR1 (0.60) | OPRK1SIGMAR1MEN1KMT2ACA12 | |
| SCHEMBL28968728 | 0.80 | SIGMAR1 (0.64) | SIGMAR1CA12CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | ABBVIE PHARMACEUTICAL TRADING (SHANGHAI) CO., LTD. (CN) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | LPAR1, LPAR3, LPAR2 | OPRK1 720/4885SIGMAR1 233/4885MEN1 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.