SCHEMBL2091673

SCHEMBL2091673

Cc1ccc(N(C)C=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
TSHR P16473 2/20 0.52
CYP2A6 P11509 2/20 0.44
MAPT P10636 2/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
TDP1 Q9NUW8 3/20 0.40
ACHE P22303 1/20 0.40
CYP2A13 Q16696 1/20 0.39
POLB P06746 1/20 0.37
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
GFER P55789 1/20 0.36
MCL1 Q07820 1/20 0.36
RAB9A P51151 1/20 0.36
CHRNA7 P36544 1/20 0.36
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031222 0.80 CYP2A6 (0.39) ALDH1A1TSHRCYP2A6MAPTCYP2A13
P-Xylene SCHEMBL4351291 0.78 TSHR (0.56) ALDH1A1TSHRCYP2A6MAPTMCOLN3
SCHEMBL11098248 0.78 CYP2A6 (0.67) ALDH1A1CYP2A6CYP2A13HSD17B10
SCHEMBL203434 0.78 CYP2A6 (0.38) ALDH1A1TSHRCYP2A6CYP2A13GAA
SCHEMBL2099516 0.78 APP (0.48) ALDH1A1TSHRCYP2A6MAPTCYP2A13
SCHEMBL9512083 0.78 ALDH1A1 (0.54) ALDH1A1TSHRCYP2A6MAPTTDP1
SCHEMBL1031223 0.78 APP (0.48) ALDH1A1CYP2A6MAPTTDP1ACHE
SCHEMBL2090725 0.78 MAPT (0.40) ALDH1A1TSHRCYP2A6MAPTTDP1
SCHEMBL2096460 0.78 ALDH1A1 (0.45) ALDH1A1TSHRCYP2A6MAPTTDP1
SCHEMBL14093915 0.78 CYP2A6 (0.38) ALDH1A1TSHRCYP2A6CYP2A13ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908853-A Method for preparing (E) -2-amino functionalized-3-diaryl substituted acrylonitrile compound 湖南理工学院 2024-11-08 CN claimed
CN-118908853-A Method for preparing (E) -2-amino functionalized-3-diaryl substituted acrylonitrile compound 湖南理工学院 2024-11-08 CN disclosed
WO-2022026565-A1 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2022-02-03 WO disclosed
CN-109824465-B Method for synthesizing amide by amine oxide catalyzed by bipyridine manganese catalyst 陕西师范大学 2022-01-04 CN disclosed
CN-108774147-B N-aryl formamide prepared by taking bromodifluoroacetic acid ethyl ester as formylation reagent 温州大学 2021-01-08 CN disclosed
CN-108774147-A A kind of N- aryl carboxamides prepared as formylation reagent using bromo difluoro acetate ethyl ester 温州大学 2018-11-09 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
EP-1975160-B1 Polymerizable compound, polymer, ink composition, printed articles and inkjet recording method FUJIFILM CORP (JP) 2013-01-16 EP disclosed
US-8173226-B2 Polymerizable compound , polyethylene glycol mono(meth)acrylate, a polystyrene oligomer having a methacryloyl group at one terminal, acrylic macromonomer imides FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US disclosed
US-5213897-A Curable coating compositions containing an N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazide ELF ATOCHEM NORTH AMERICA, INC. 1993-05-25 US disclosed
EP-0507333-A2 Epoxy resins containing bound light stabilizing groups ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-10-07 EP disclosed
EP-0287675-B1 PROCESS FOR PRODUCING BIPHENOLS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-01-02 EP disclosed
WO-1991011448-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-08 WO disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
US-4902837-A OXIDATION COUPLING OF PHENOLS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-02-20 US disclosed
EP-0287675-A1 PROCESS FOR PRODUCING BIPHENOLS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-26 EP disclosed
US-4195999-A Silver halide photographic material containing ultraviolet light absorbing agent FUJI PHOTO FILM CO., LTD. (JP) 1980-04-01 US disclosed
US-4163671-A PYRROLIDINE OR THIAZOLIDINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1979-08-07 US disclosed