P-Xylene

P-Xylene

SCHEMBL4351291

CN(C)C=O.Cc1ccc(C)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
CYP2A6 P11509 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
ACHE P22303 2/20 0.50
ALDH1A1 P00352 5/20 0.48
LMNA P02545 3/20 0.45
GAA P10253 2/20 0.45
CHRNA7 P36544 1/20 0.42
PKM P14618 2/20 0.40
HTT P42858 2/20 0.40
ATM Q13315 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NLRP1 Q9C000 1/20 0.40
TLR9 Q9NR96 1/20 0.40
NTSR1 P30989 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAP1LC3B Q9GZQ8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cresol SCHEMBL9173079 0.87 ACHE (0.62) TSHRCYP2A6TDP1ACHEALDH1A1
P-Xylene SCHEMBL28282224 0.87 TSHR (0.43) TSHRCYP2A6TDP1ACHEALDH1A1
Dimethylformamide SCHEMBL28315070 0.87 CES2 (0.50) TSHRCYP2A6ACHEALDH1A1LMNA
Toluene SCHEMBL514424 0.86 TSHR (0.58) TSHRCYP2A6ACHEALDH1A1LMNA
Toluene SCHEMBL437949 0.84 TSHR (0.55) TSHRCYP2A6ACHEALDH1A1LMNA
Dimethylformamide SCHEMBL28882249 0.83 CYP2A6 (0.39) TSHRCYP2A6TDP1ACHEALDH1A1
Toluene SCHEMBL28765894 0.82 TSHR (0.52) TSHRCYP2A6ACHEALDH1A1LMNA
Dimethylformamide SCHEMBL9300360 0.81 TSHR (0.56) TSHRCYP2A6TDP1ACHEALDH1A1
SCHEMBL2091673 0.78 ALDH1A1 (0.52) TSHRCYP2A6TDP1ACHEALDH1A1
O-Xylene SCHEMBL10797227 0.77 TSHR (0.56) TSHRCYP2A6TDP1ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892613-B A kind of new R-9-(2-hydroxypropyl) the purification process technique of adenine 洛阳德胜生物科技股份有限公司 2016-06-29 CN claimed
CN-110494470-A Polyester resin and its solidfied material DAINIPPON INK & CHEMICALS 2019-11-22 CN disclosed
CN-110475798-A Active ester composition DAINIPPON INK & CHEMICALS 2019-11-19 CN disclosed
CN-110461920-A Etching solution and etching method for resin composition MITSUBISHI PAPER MILLS LTD 2019-11-15 CN disclosed
CN-110387155-A Resin combination 味之素株式会社 2019-10-29 CN disclosed
CN-110387154-A Resin combination 味之素株式会社 2019-10-29 CN disclosed
CN-110383946-A Sealing sheet 味之素株式会社 2019-10-25 CN disclosed
CN-106661017-B Bicyclic or tricyclic heterocyclic compounds 田边三菱制药株式会社 2019-09-24 CN disclosed
CN-106465505-B The manufacturing method of seal 味之素株式会社 2019-09-20 CN disclosed
CN-106573945-B Hybrid flame retardant based on DOPO 瑞士材料试验研究所 2019-08-23 CN disclosed
WO-1987003606-A1 OLEFINIC CHLOROSILANE AND OLEFINIC HALIDE FUNCTIONAL GROUP CONTAINING POLYMERS AND METHOD OF FORMING THE SAME EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-06-18 WO disclosed
EP-0204842-A4 NODULAR COPOLYMERS FORMED OF ALPHA-OLEFIN COPOLYMERS COUPLED BY NON-CONJUGATED DIENES. EXXON RESEARCH ENGINEERING CO (US) 1987-04-28 EP disclosed
EP-0204842-A1 NODULAR COPOLYMERS FORMED OF ALPHA-OLEFIN COPOLYMERS COUPLED BY NON-CONJUGATED DIENES. EXXON RESEARCH ENGINEERING CO (US) 1986-12-17 EP disclosed
EP-0204840-A1 MOLECULAR WEIGHT DISTRIBUTION MODIFICATION IN TUBULAR REACTOR EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-12-17 EP disclosed
WO-1986003756-A1 MOLECULAR WEIGHT DISTRIBUTION MODIFICATION IN TUBULAR REACTOR EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-07-03 WO disclosed
WO-1986003755-A1 NODULAR COPOLYMERS FORMED OF ALPHA-OLEFIN COPOLYMERS COUPLED BY NON-CONJUGATED DIENES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-07-03 WO disclosed
US-4540753-A COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-09-10 US disclosed
EP-0129414-A2 Narrow MWD alpha-olefin copolymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-12-27 EP disclosed
US-4002794-A BLOC4002794 MOD 4002794 K POLYMER FROM MERCAPTOALKYL TERMINATED POLYDIMETHYL SILOXANE AND DIISOCYA NASHUA CORPORATION (US) 1977-01-11 US disclosed
US-3935362-A Image control means and structured transfer sheet for thermal reproduction processes BELL & HOWELL COMPANY (US) 1976-01-27 US disclosed