Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 15/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938188 | 1.00 | ADK (0.47) | ADKPRMT5METTL3DOT1LNPC1 | |
| SCHEMBL1737471 | 0.85 | ADK (0.60) | ADKPRMT5METTL3DOT1LNPC1 | |
| SCHEMBL6731807 | 0.85 | ADK (0.60) | ADKPRMT5METTL3DOT1LNPC1 | |
| SCHEMBL3768787 | 0.84 | ADK (0.61) | ADKPRMT5DOT1LNPC1GALR3 | |
| SCHEMBL20419264 | 0.84 | ADK (0.61) | ADKPRMT5DOT1LNPC1GALR3 | |
| SCHEMBL22912603 | 0.84 | PRMT5 (0.48) | ADKPRMT5METTL3DOT1LNPC1 | |
| SCHEMBL20938262 | 0.84 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL13068771 | 0.84 | ADK (0.61) | ADKPRMT5DOT1LNPC1GALR3 | |
| SCHEMBL20938333 | 0.84 | ADK (0.46) | ADKPRMT5METTL3DOT1LNPC1 | |
| SCHEMBL20419136 | 0.84 | ADK (0.59) | ADKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697800-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | Universiteit Gent (BE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |