Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | RNMT | O43148 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938256 | 1.00 | ADK (0.48) | ADKDOT1LADORA3ADORA2ARNMT | |
| SCHEMBL20938191 | 0.84 | ADK (0.67) | ADKDOT1LABL1 | |
| SCHEMBL1738494 | 0.84 | ADK (0.61) | ADKDOT1L | |
| SCHEMBL6732487 | 0.84 | ADK (0.61) | ADKDOT1L | |
| SCHEMBL20916992 | 0.83 | ADK (0.63) | ADKABL1EGFRABL2SRC | |
| SCHEMBL22912604 | 0.83 | ADK (0.63) | ADKABL1EGFRABL2SRC | |
| SCHEMBL20938257 | 0.83 | ADK (0.48) | ADKDOT1LADORA3 | |
| SCHEMBL20938249 | 0.81 | ADK (0.47) | ADKDOT1LADORA3ADORA2A | |
| SCHEMBL20938186 | 0.80 | ADK (0.45) | ADKDOT1LABL1EGFRABL2 | |
| SCHEMBL20938262 | 0.79 | ADK (0.59) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697800-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | Universiteit Gent (BE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |