Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920143 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL7598632 | 0.83 | EPHX1 (0.61) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17187551 | 0.83 | EPHX1 (0.61) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL19435743 | 0.83 | EPHX1 (0.61) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL5621854 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL5621851 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL5455050 | 0.79 | SMN1; SMN2 (0.88) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL9616079 | 0.78 | SIGMAR1 (0.59) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL9616080 | 0.78 | SIGMAR1 (0.59) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL5447885 | 0.78 | SMN1; SMN2 (0.84) | SMN1; SMN2LMNAMAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078116-A1 | SWEETNESS RECEPTOR ANTAGONIST | 味の素株式会社 | 2019-04-25 | — | — | WO | disclosed |