Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16891451 | 0.77 | CYP1A2 (0.46) | ALDH1A1QPCTQPCTLPSMB5EGFR | |
| SCHEMBL888951 | 0.77 | NPC1 (0.41) | SMN1; SMN2ALDH1A1NPC1SCN4ARAB9A | |
| SCHEMBL799309 | 0.77 | PSMB5 (0.41) | SMN1; SMN2ALDH1A1NPC1SCN4ARAB9A | |
| SCHEMBL16881152 | 0.76 | PRNP (0.49) | SMN1; SMN2ALDH1A1QPCTQPCTLEGFR | |
| SCHEMBL27998998 | 0.76 | NPC1 (0.40) | SMN1; SMN2ALDH1A1NPC1SCN4ARAB9A | |
| SCHEMBL26128691 | 0.76 | FTO (0.57) | QPCTQPCTLEGFRFTOHASPIN | |
| SCHEMBL2625324 | 0.76 | LCK (0.49) | SMN1; SMN2ALDH1A1NPC1SCN4ARAB9A | |
| Hydrochloric Acid SCHEMBL28105750 | 0.75 | PRNP (0.48) | SMN1; SMN2ALDH1A1QPCTQPCTLPSMB5 | |
| SCHEMBL25097413 | 0.73 | BRAF (0.43) | SMN1; SMN2NPC1SCN4ARAB9APSMB5 | |
| SCHEMBL20047504 | 0.73 | NPC1 (0.38) | SMN1; SMN2ALDH1A1NPC1SCN4ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266515-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266515-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | SMN1; SMN2 4577/4885ALDH1A1 1717/4885NPC1 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.