SCHEMBL20922355

SCHEMBL20922355

O=C(c1ccc(Cc2ccccc2)cc1)N1CCC(CN2CCC(N3CCCCC3)CC2)C1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 14/20 0.58
L3MBTL1 Q9Y468 12/20 0.58
MBTD1 Q05BQ5 7/20 0.58
TP53BP1 Q12888 1/20 0.53
L3MBTL4 Q8NA19 1/20 0.53
HRH3 Q9Y5N1 3/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18502076 0.87 L3MBTL3 (0.55) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL4765933 0.85 L3MBTL3 (0.71) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL2884997 0.85 L3MBTL3 (0.71) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
Hydrochloric Acid SCHEMBL2883905 0.84 L3MBTL3 (0.69) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL3917660 0.77 KDM4E (0.68) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23718118 0.75 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL13034197 0.74 L3MBTL3 (0.72) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL27669216 0.74 L3MBTL3 (0.94) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL10293557 0.74 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682947 0.74 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131890-B1 COMPOUNDS FOR TREATING VIRAL INFECTIONS PASTEUR INSTITUT KOREA (KR) 2019-04-24 EP disclosed