Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.64 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.63 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.61 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884997 | 1.00 | L3MBTL3 (0.71) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL2883905 | 0.99 | L3MBTL3 (0.69) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL20922355 | 0.85 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL13085892 | 0.84 | L3MBTL3 (0.74) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL2881922 | 0.84 | L3MBTL3 (0.74) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL3917660 | 0.83 | KDM4E (0.68) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL1735125 | 0.82 | L3MBTL3 (0.71) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL3841287 | 0.82 | L3MBTL3 (0.71) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL693648 | 0.82 | KDM4E (0.56) | L3MBTL3L3MBTL1HRH3MBTD1 | |
| SCHEMBL2881466 | 0.81 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | disclosed |