SCHEMBL20923155

SCHEMBL20923155

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccncc3)c(C#N)cc2-c2ccccc2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
CYP2C19 P33261 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
SQOR Q9Y6N5 1/20 0.34
XDH P47989 2/20 0.34
HPGD P15428 2/20 0.34
PDE5A O76074 1/20 0.34
TSHR P16473 1/20 0.34
PTGS1 P23219 1/20 0.34
PDE4A P27815 1/20 0.34
BLM P54132 1/20 0.34
PDE4B Q07343 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20923157 0.97 KDM4E (0.38) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923596 0.96 ALDH1A1 (0.38) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923548 0.94 ALDH1A1 (0.36) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923602 0.93 NPSR1 (0.40) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL22170307 0.93 XDH (0.36) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL22019653 0.93 KDM4E (0.35) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923150 0.93 KDM4E (0.33) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923534 0.92 AR (0.38) NPSR1KDM4ELMNAALDH1A1CYP2C19
SCHEMBL20923550 0.92 NPSR1 (0.38) NPSR1KDM4ELMNAALDH1A1MEN1
SCHEMBL20923130 0.91 KDM4E (0.43) NPSR1KDM4ELMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266772-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-04-24 EP disclosed