Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923265 | 0.97 | PIK3CA (0.43) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL20924108 | 0.96 | MAPK13 (0.39) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL20923530 | 0.96 | PIK3CA (0.43) | PIK3CAPRKACACDK8CLK2GSK3A | |
| SCHEMBL20923762 | 0.94 | PIK3CA (0.38) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL20923271 | 0.93 | PIK3CA (0.37) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL20923543 | 0.93 | CYP19A1 (0.39) | MAPK14MAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL20924116 | 0.93 | MAPK13 (0.41) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL19909032 | 0.93 | PTGER4 (0.38) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL19919784 | 0.93 | PTGER4 (0.38) | PIK3CAMAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL20923142 | 0.92 | CYP19A1 (0.38) | PIK3CAMAPK14MAPK13RAF1MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |