SCHEMBL19919784

SCHEMBL19919784

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccncc3)c(-n3c4ccccc4c4cc(-c5ccc(C#N)cc5)ccc43)cc2C#N)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.38
FLT3 P36888 2/20 0.37
MAPK14 Q16539 2/20 0.36
GSK3B P49841 2/20 0.36
MAPK13 O15264 1/20 0.36
RAF1 P04049 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
PRKACA P17612 1/20 0.36
CDK8 P49336 1/20 0.36
CLK2 P49760 1/20 0.36
GSK3A P49840 1/20 0.36
CDK9 P50750 1/20 0.36
CDK5 Q00535 1/20 0.36
PRKCQ Q04759 1/20 0.36
ROCK1 Q13464 1/20 0.36
DYRK1A Q13627 1/20 0.36
LRRK2 Q5S007 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
DYRK1B Q9Y463 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919766 0.96 FLT3 (0.39) FLT3MAPK14GSK3BMAPK13RAF1
SCHEMBL19909032 0.94 PTGER4 (0.38) PTGER4FLT3MAPK14GSK3BMAPK13
SCHEMBL19919781 0.94 FLT3 (0.39) FLT3MAPK14GSK3BMAPK13RAF1
SCHEMBL19909483 0.93 PIK3CA (0.41) GSK3BPRKACACDK8CLK2GSK3A
SCHEMBL20924108 0.93 MAPK13 (0.39) PTGER4FLT3MAPK14GSK3BMAPK13
SCHEMBL20923264 0.93 PIK3CA (0.40) PTGER4FLT3MAPK14GSK3BMAPK13
SCHEMBL19909157 0.93 SQOR (0.34) PTGER4FLT3MAPK14GSK3BPRKACA
SCHEMBL19909084 0.92 CYP19A1 (0.38) PTGER4FLT3LRRK2CYP11B2SQOR
SCHEMBL19919464 0.92 USP2 (0.40) PTGER4MAPK14GSK3BGSK3AROCK1
SCHEMBL19909296 0.91 PIK3CA (0.43) GSK3BPRKACACDK8CLK2GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 PTGER4 1123/4885FLT3 2571/4885MAPK14 2544/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 PTGER4 1386/4885FLT3 3269/4885MAPK14 2787/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 PTGER4 1123/4885FLT3 2571/4885MAPK14 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.