Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 7/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923231 | 0.95 | CYP11B1 (0.40) | CYP11B1CYP11B2ARGPBAR1METAP2 | |
| SCHEMBL20923731 | 0.94 | CYP11B1 (0.36) | CYP11B1CYP11B2ARGPBAR1METAP2 | |
| SCHEMBL20924082 | 0.92 | METAP2 (0.35) | CYP11B1CYP11B2ARGPBAR1METAP2 | |
| SCHEMBL21131416 | 0.91 | AR (0.38) | CYP11B1CYP11B2AR | |
| SCHEMBL20924037 | 0.90 | CYP19A1 (0.38) | CYP11B1CYP11B2ARGPBAR1METAP2 | |
| SCHEMBL20923736 | 0.89 | CYP11B1 (0.40) | CYP11B1CYP11B2GPBAR1METAP2EPHX2 | |
| SCHEMBL21758251 | 0.88 | GPBAR1 (0.36) | CYP11B1CYP11B2ARGPBAR1 | |
| SCHEMBL22170431 | 0.87 | METAP2 (0.37) | CYP11B1CYP11B2GPBAR1METAP2EPHX2 | |
| SCHEMBL20923672 | 0.87 | CYP11B1 (0.37) | CYP11B1CYP11B2GPBAR1METAP2 | |
| SCHEMBL20923101 | 0.87 | GSK3B (0.41) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |