Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923731 | 0.95 | CYP11B1 (0.36) | CYP11B1CYP11B2METAP2EPHX2GPBAR1 | |
| SCHEMBL20923231 | 0.92 | CYP11B1 (0.40) | CYP11B1CYP11B2METAP2SRCBRAF | |
| SCHEMBL20924077 | 0.92 | METAP2 (0.38) | CYP11B1CYP11B2METAP2SRCBRAF | |
| SCHEMBL21131806 | 0.90 | CYP11B1 (0.40) | CYP11B1CYP11B2KIF11LMNAHPGD | |
| SCHEMBL20923463 | 0.89 | CYP11B1 (0.36) | CYP11B1CYP11B2METAP2EPHX2GPBAR1 | |
| SCHEMBL20924034 | 0.89 | METAP2 (0.40) | CYP11B1CYP11B2METAP2SRCBRAF | |
| SCHEMBL20924087 | 0.87 | METAP2 (0.35) | CYP11B1CYP11B2METAP2EPHX2GPBAR1 | |
| SCHEMBL19919773 | 0.86 | METAP2 (0.40) | CYP11B1CYP11B2METAP2KIF11S1PR1 | |
| SCHEMBL20924088 | 0.86 | AR (0.37) | CYP11B1CYP11B2METAP2SRCBRAF | |
| SCHEMBL21131804 | 0.85 | AR (0.38) | CYP11B1CYP11B2KIF11LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |