Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2228922 | 0.85 | NPC1 (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL59309 | 0.84 | RAB9A (0.61) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL29363181 | 0.84 | RAB9A (0.61) | ALDH1A1KDM4EHPGDCA12CA2 | |
| Phenyl Salicylate SCHEMBL28140255 | 0.83 | HPGD (0.65) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| Methane SCHEMBL10729260 | 0.82 | RAB9A (0.59) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL5166388 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDCA12CA1 | |
| Phthalic Acid SCHEMBL1162068 | 0.78 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDCA12CA1 | |
| Salicylic Acid SCHEMBL29629300 | 0.78 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL9189375 | 0.78 | POLB (0.47) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL17296033 | 0.77 | NPC1 (0.51) | ALDH1A1KDM4EHPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194324-A | Trans, trans-diketoxime ester isomer and its preparing method and use | 北京英力科技发展有限公司 | 2020-05-22 | — | — | CN | disclosed |
| WO-2019076145-A1 | TRANS, TRANS-DIKETONE OXIME ESTER ISOMER, MANUFACTURING METHOD THEREFOR AND APPLICATION THEREOF | 北京英力科技发展有限公司 | 2019-04-25 | — | — | WO | disclosed |
| CN-103387765-B | Photosensitive composition for solder resist printing ink or photoresist | INSIGHT HIGH TECHNOLOGY BEIJING CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-103387765-A | Photosensitive composition for solder resist printing ink or photoresist | BEIJING INSIGHT HIGH TECHNOLOGY CO LTD | 2013-11-13 | — | — | CN | disclosed |