Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924084 | 0.94 | CYP19A1 (0.40) | FLT3CYP19A1CYP11B1CYP11B2PTGER4 | |
| SCHEMBL20923110 | 0.94 | PIK3CA (0.41) | CYP19A1GSK3BPRKACACDK8CLK2 | |
| SCHEMBL20923180 | 0.93 | CYP19A1 (0.35) | FLT3CYP19A1CYP11B1CYP11B2GSK3B | |
| SCHEMBL20923704 | 0.92 | CYP19A1 (0.42) | FLT3CYP19A1CYP11B1CYP11B2PTGER4 | |
| SCHEMBL20923661 | 0.92 | FLT3 (0.39) | FLT3CYP19A1CYP11B1CYP11B2PTGER4 | |
| SCHEMBL20923617 | 0.90 | PIK3CA (0.43) | CYP19A1CYP11B1CYP11B2GSK3BPRKACA | |
| SCHEMBL20923374 | 0.90 | LMNA (0.39) | CYP19A1CYP11B1CYP11B2MAPK14ALDH1A1 | |
| SCHEMBL20923296 | 0.90 | LMNA (0.39) | CYP19A1CYP11B1CYP11B2MAPK14ALDH1A1 | |
| SCHEMBL20923694 | 0.89 | FLT3 (0.41) | FLT3CYP19A1CYP11B1CYP11B2GSK3B | |
| SCHEMBL20924076 | 0.88 | STS (0.40) | FLT3CYP19A1CYP11B1CYP11B2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |