SCHEMBL20923296

SCHEMBL20923296

N#Cc1cc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)ccc1-c1ccncc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP19A1 P11511 2/20 0.36
SQOR Q9Y6N5 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
XDH P47989 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
METAP2 P50579 1/20 0.35
KDM4E B2RXH2 2/20 0.35
PDE5A O76074 1/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
PDE4B Q07343 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20923374 1.00 LMNA (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923704 0.93 CYP19A1 (0.42) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923305 0.93 LMNA (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923307 0.93 LMNA (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923110 0.92 PIK3CA (0.41) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923737 0.90 LMNA (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923751 0.90 LMNA (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20924084 0.90 CYP19A1 (0.40) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL20923693 0.90 FLT3 (0.39) LMNAHPGDALDH1A1MAPK1SMN1; SMN2
SCHEMBL19908986 0.89 SQOR (0.36) LMNAHPGDALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266772-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-04-24 EP disclosed