Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923256 | 0.97 | PIK3CA (0.37) | METAP2PIK3CAGPBAR1EPHX2MAPK14 | |
| SCHEMBL20923847 | 0.96 | METAP2 (0.36) | METAP2PIK3CAGPBAR1EPHX2MAPK14 | |
| SCHEMBL20923274 | 0.94 | METAP2 (0.36) | METAP2PIK3CAGPBAR1EPHX2MAPK14 | |
| SCHEMBL20923601 | 0.93 | GPBAR1 (0.36) | METAP2PIK3CAGPBAR1EPHX2MAPK14 | |
| SCHEMBL19919458 | 0.93 | CYP11B1 (0.35) | METAP2GPBAR1EPHX2MAPK14CYP11B1 | |
| SCHEMBL22170431 | 0.93 | METAP2 (0.37) | METAP2GPBAR1EPHX2MAPK14CYP11B1 | |
| SCHEMBL20923768 | 0.92 | METAP2 (0.37) | METAP2PIK3CAGPBAR1EPHX2CYP11B1 | |
| SCHEMBL20924144 | 0.91 | METAP2 (0.36) | METAP2GPBAR1EPHX2MAPK14CYP11B1 | |
| SCHEMBL20923118 | 0.91 | METAP2 (0.38) | METAP2GPBAR1EPHX2MAPK14CYP11B1 | |
| SCHEMBL20923773 | 0.90 | METAP2 (0.35) | METAP2GPBAR1EPHX2MAPK14CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |