Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923763 | 0.96 | PTGER4 (0.38) | PTGER4CYP11B1CYP11B2MAPK14FLT3 | |
| SCHEMBL20924115 | 0.95 | CYP11B2 (0.39) | CYP11B1CYP11B2MAPK14FLT3AAK1 | |
| SCHEMBL20923681 | 0.94 | CHEK1 (0.37) | PTGER4CYP11B1CYP11B2MAPK14FLT3 | |
| SCHEMBL20923631 | 0.93 | PTGER4 (0.35) | PTGER4CYP11B1CYP11B2MAPK14SQOR | |
| SCHEMBL20923188 | 0.93 | PTGER4 (0.38) | PTGER4CYP11B1CYP11B2SQORXDH | |
| SCHEMBL20923836 | 0.92 | CYP11B1 (0.39) | PTGER4CYP11B1CYP11B2FLT3SQOR | |
| SCHEMBL19909032 | 0.92 | PTGER4 (0.38) | PTGER4CYP11B1CYP11B2MAPK14FLT3 | |
| SCHEMBL20923262 | 0.91 | CYP2C19 (0.37) | CYP11B1CYP11B2MAPK14FLT3AAK1 | |
| SCHEMBL20924046 | 0.91 | PIK3CA (0.41) | SQORAAK1GSK3BCHEK1MKNK1 | |
| SCHEMBL20923766 | 0.90 | CHEK1 (0.37) | PTGER4CYP11B1CYP11B2MAPK14FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |