Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923681 | 0.96 | CHEK1 (0.37) | CHEK1FLT3LMNATSHRKDM4E | |
| SCHEMBL20923764 | 0.95 | CHEK1 (0.40) | CHEK1FLT3LMNATSHRKDM4E | |
| SCHEMBL20923763 | 0.94 | PTGER4 (0.38) | CHEK1FLT3LMNATSHRKDM4E | |
| SCHEMBL20923089 | 0.94 | IMPDH2 (0.38) | LMNATSHRKDM4EPDE5AHPGD | |
| SCHEMBL20923081 | 0.93 | CYP11B1 (0.36) | FLT3LMNATSHRKDM4EPDE5A | |
| SCHEMBL20923735 | 0.92 | CYP11B1 (0.36) | FLT3LMNATSHRKDM4EPDE5A | |
| SCHEMBL19909025 | 0.92 | FLT3 (0.39) | CHEK1FLT3PRKACACDK8CLK2 | |
| SCHEMBL20923811 | 0.91 | CHEK1 (0.40) | CHEK1FLT3LMNATSHRKDM4E | |
| SCHEMBL20923795 | 0.90 | PTGER4 (0.40) | CHEK1FLT3LMNATSHRKDM4E | |
| SCHEMBL20923560 | 0.90 | SQOR (0.40) | CHEK1LMNATSHRKDM4EPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |