Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.67 |
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924184 | 0.86 | KDM1A (0.68) | KDM1AMAOBHTR2CDGAT1MAOA | |
| SCHEMBL20924268 | 0.82 | KDM1A (0.70) | KDM1AMAOBHTR2CMAOA | |
| Ammonia Solution, Strong SCHEMBL526934 | 0.81 | KDM1A (0.68) | KDM1AMAOBHTR2CMAOA | |
| SCHEMBL528016 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL528017 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL17512871 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL15136756 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL20923927 | 0.80 | KDM1A (0.71) | KDM1AMAOBDGAT1MAOA | |
| Hydrochloric Acid SCHEMBL15136202 | 0.79 | KDM1A (0.97) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15136201 | 0.79 | KDM1A (0.97) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |