Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.68 |
| ▸ | MAOB | P27338 | 8/20 | 0.68 |
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924268 | 0.99 | KDM1A (0.70) | KDM1AMAOBMAOAMEN1POLB | |
| SCHEMBL20924184 | 0.85 | KDM1A (0.68) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL21840989 | 0.81 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL527203 | 0.81 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL526935 | 0.81 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL13975824 | 0.81 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL20923893 | 0.81 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2C | |
| Hydrochloric Acid SCHEMBL527129 | 0.80 | KDM1A (0.97) | KDM1AMAOBMAOA | |
| Hydrochloric Acid SCHEMBL527128 | 0.80 | KDM1A (0.97) | KDM1AMAOBMAOA | |
| SCHEMBL20923927 | 0.80 | KDM1A (0.71) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2013-06-05 | — | — | EP | claimed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | claimed |