Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.71 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924184 | 0.90 | KDM1A (0.68) | KDM1AMAOBMAOADGAT1NOTUM | |
| SCHEMBL527494 | 0.83 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL6837360 | 0.83 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL527495 | 0.83 | KDM1A (1.00) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15136684 | 0.82 | KDM1A (0.98) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15136683 | 0.82 | KDM1A (0.98) | KDM1AMAOB | |
| SCHEMBL20924262 | 0.82 | KDM1A (0.69) | KDM1AMAOB | |
| SCHEMBL21945524 | 0.81 | KDM1A (0.63) | KDM1AMAOB | |
| SCHEMBL20924268 | 0.81 | KDM1A (0.70) | KDM1AMAOBMAOA | |
| SCHEMBL20924271 | 0.81 | KDM1A (0.53) | KDM1AMAOBMAOADGAT1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |