Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924093 | 0.87 | KDM1A (0.50) | KDM1AMAOBDGAT1MAOA | |
| SCHEMBL20924184 | 0.87 | KDM1A (0.68) | KDM1AMAOBDGAT1MAOANOTUM | |
| SCHEMBL20923927 | 0.81 | KDM1A (0.71) | KDM1AMAOBDGAT1MAOANOTUM | |
| SCHEMBL20924215 | 0.80 | KDM1A (0.73) | KDM1AMAOBMAOA | |
| SCHEMBL20924268 | 0.78 | KDM1A (0.70) | KDM1AMAOBMAOA | |
| SCHEMBL20923973 | 0.78 | KDM1A (0.55) | KDM1AMAOBDGAT1MAOA | |
| SCHEMBL20923893 | 0.77 | KDM1A (0.67) | KDM1AMAOBDGAT1MAOAMCHR1 | |
| Ammonia Solution, Strong SCHEMBL526934 | 0.76 | KDM1A (0.68) | KDM1AMAOBMAOA | |
| SCHEMBL28637837 | 0.75 | NOTUM (0.43) | NOTUM | |
| SCHEMBL527803 | 0.71 | KDM1A (0.72) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |