Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.69 |
| ▸ | LDHA | P00338 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924009 | 0.82 | KDM1A (0.69) | KDM1AMAOB | |
| SCHEMBL527345 | 0.82 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL527344 | 0.82 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL6837340 | 0.82 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL20923927 | 0.82 | KDM1A (0.71) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL529690 | 0.81 | KDM1A (0.97) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL529689 | 0.81 | KDM1A (0.97) | KDM1AMAOB | |
| SCHEMBL20924186 | 0.79 | KDM1A (0.48) | KDM1A | |
| SCHEMBL20924166 | 0.79 | KDM1A (0.71) | KDM1ALDHADHODH | |
| SCHEMBL20019597 | 0.79 | KDM1A (0.68) | KDM1AMAOBHSD17B1HSD17B2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |