Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838740 | 0.83 | NOTUM (0.46) | PDGFRBPDGFRACLK4DYRK1A | |
| SCHEMBL15136353 | 0.82 | KDM1A (0.63) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| SCHEMBL7694556 | 0.82 | KDM1A (0.63) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| SCHEMBL527143 | 0.82 | KDM1A (0.63) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| SCHEMBL15137194 | 0.82 | KDM1A (0.63) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| SCHEMBL527144 | 0.82 | KDM1A (0.63) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| Hydrochloric Acid SCHEMBL527781 | 0.81 | KDM1A (0.62) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| Hydrochloric Acid SCHEMBL527780 | 0.81 | KDM1A (0.62) | PDGFRBPDGFRACLK4DYRK1AFYN | |
| SCHEMBL23601916 | 0.80 | NOTUM (0.44) | KDM1AMAP4K4 | |
| SCHEMBL20923972 | 0.77 | HSD17B1 (0.63) | DYRK1AFYNKDM1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |