Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601694 | 0.81 | KDM1A (0.50) | KDM1AIDO1METAP2CASP3SENP7 | |
| SCHEMBL20923972 | 0.81 | HSD17B1 (0.63) | NOTUMKDM1AMETAP2 | |
| SCHEMBL24721517 | 0.80 | IDO1 (0.46) | NOTUMDRD4DRD2IDO1GRIN2B | |
| SCHEMBL20923957 | 0.80 | PDGFRB (0.48) | KDM1AMAP4K4 | |
| SCHEMBL24721007 | 0.80 | RXRA (0.43) | NOTUMIDO1MAP3K5PTGS1PTGS2 | |
| SCHEMBL4404645 | 0.79 | HSD17B1 (0.55) | KDM1AENPP3IDO1METAP2MAP4K4 | |
| SCHEMBL23601705 | 0.79 | KDM1A (0.48) | KDM1AIDO1METAP2CASP3SENP7 | |
| SCHEMBL5564612 | 0.77 | CLK4 (0.47) | KDM1AIDO1MAP4K4 | |
| SCHEMBL4406991 | 0.76 | HSD17B1 (0.51) | KDM1AENPP3IDO1METAP2MAP4K4 | |
| SCHEMBL4402515 | 0.76 | HSD17B1 (0.61) | KDM1AENPP3IDO1METAP2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |