Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457300 | 0.85 | KDM1A (0.49) | KDM1AMAOAFPR2PDE4APDE4B | |
| SCHEMBL16554269 | 0.83 | MAOB (0.53) | KDM1AMAOACYP3A4ESR1ESR2 | |
| SCHEMBL530324 | 0.81 | KDM1A (1.00) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL530325 | 0.81 | KDM1A (1.00) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL6837446 | 0.81 | KDM1A (1.00) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| Hydrochloric Acid SCHEMBL527346 | 0.80 | KDM1A (0.97) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| Hydrochloric Acid SCHEMBL15136850 | 0.80 | KDM1A (0.97) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL29431753 | 0.77 | KDM1A (0.57) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL29431787 | 0.76 | HSD17B1 (0.59) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 | |
| SCHEMBL22954804 | 0.76 | CYP3A4 (0.69) | KDM1AMAOAHSD17B1HSD17B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |