Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923971 | 0.85 | KDM1A (0.68) | KDM1AMAOAHTR2CPDE4APDE4B | |
| SCHEMBL458343 | 0.77 | NOTUM (0.48) | KDM1AHTR2C | |
| SCHEMBL5961843 | 0.76 | CYP3A4 (0.53) | HTR2CKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1515163 | 0.75 | HTR2C (0.75) | HTR2CKMT2AMEN1 | |
| SCHEMBL4533772 | 0.75 | L3MBTL1 (0.62) | PDE4AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL23268487 | 0.74 | MEN1 (0.58) | HTR2CKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3692141 | 0.74 | MEN1 (0.58) | HTR2CKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12180448 | 0.74 | ACHE (0.54) | HTR2CKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL31172738 | 0.74 | MEN1 (0.58) | HTR2CKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL18123010 | 0.73 | HTR2C (0.43) | HTR2CKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |