Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924009 | 0.89 | KDM1A (0.69) | KDM1AMAOBMAOAGRM5DGAT1 | |
| SCHEMBL20923991 | 0.85 | KDM1A (0.71) | KDM1AMAOBMAOAGRM5 | |
| SCHEMBL20923954 | 0.85 | KDM1A (0.68) | KDM1AMAOBGRM5 | |
| SCHEMBL20924267 | 0.84 | KDM1A (0.64) | KDM1AMAOBDGAT1 | |
| SCHEMBL526689 | 0.79 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL6837361 | 0.79 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| SCHEMBL526688 | 0.79 | KDM1A (1.00) | KDM1AMAOBMAOA | |
| Hydrochloric Acid SCHEMBL527081 | 0.78 | KDM1A (0.97) | KDM1AMAOBMAOA | |
| Hydrochloric Acid SCHEMBL527080 | 0.78 | KDM1A (0.97) | KDM1AMAOBMAOA | |
| SCHEMBL20924257 | 0.77 | LDHA (0.46) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |