Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653265 | 0.83 | CNR1 (0.61) | HSD17B10ALOX5GPR84CNR1CNR2 | |
| SCHEMBL2034343 | 0.80 | TSHR (0.86) | HSD17B10TSHRRARBALDH1A1 | |
| SCHEMBL10456991 | 0.80 | TSHR (0.86) | HSD17B10TSHRRARBALDH1A1 | |
| SCHEMBL29290906 | 0.79 | CNR1 (0.71) | HSD17B10TSHRKDM1AMAOAALOX5 | |
| SCHEMBL23864186 | 0.79 | TSHR (0.52) | HSD17B10TSHRKDM1AGPR84RARB | |
| SCHEMBL3854168 | 0.78 | TSHR (0.62) | HSD17B10TSHRKDM1ACNR1CNR2 | |
| SCHEMBL7208756 | 0.78 | TSHR (0.62) | HSD17B10TSHRKDM1ACNR1CNR2 | |
| SCHEMBL3753968 | 0.78 | HSD17B10 (0.76) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL9818748 | 0.77 | ALOX5 (0.58) | HSD17B10ALOX5GPR84CNR1CNR2 | |
| SCHEMBL10606870 | 0.77 | TSHR (0.65) | HSD17B10TSHRCNR1CNR2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |