Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864155 | 0.81 | CTRC (0.49) | LTB4R2RARBGPR84BRS3DHODH | |
| SCHEMBL23864215 | 0.79 | POLB (0.44) | TSHRHSD17B10THRATHRB | |
| SCHEMBL20924365 | 0.79 | HSD17B10 (0.57) | TSHRHSD17B10RARBGPR84KDM1A | |
| SCHEMBL2034343 | 0.75 | TSHR (0.86) | TSHRHSD17B10RARBHRH3 | |
| SCHEMBL10456991 | 0.75 | TSHR (0.86) | TSHRHSD17B10RARBHRH3 | |
| SCHEMBL10824712 | 0.75 | HSD17B10 (0.68) | TSHRHSD17B10RARBGPR84 | |
| SCHEMBL11035358 | 0.74 | HSD17B10 (0.57) | TSHRHSD17B10RARB | |
| SCHEMBL20152480 | 0.74 | TSHR (0.62) | TSHRHSD17B10RARBKDM1AHRH3 | |
| SCHEMBL7208756 | 0.74 | TSHR (0.62) | TSHRHSD17B10RARBKDM1A | |
| SCHEMBL3854168 | 0.74 | TSHR (0.62) | TSHRHSD17B10RARBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |