Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924712 | 0.99 | NAAA (0.57) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL27594966 | 0.89 | NAAA (0.65) | NAAASMN1; SMN2HTTCYP2C19ALDH1A1 | |
| SCHEMBL16376200 | 0.86 | NAAA (0.55) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL15026848 | 0.86 | NAAA (0.55) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL15009576 | 0.86 | NAAA (0.55) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL15009586 | 0.84 | NAAA (0.54) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL15027493 | 0.84 | NAAA (0.54) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL31323892 | 0.84 | NAAA (0.52) | NAAASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL16380613 | 0.83 | NAAA (0.69) | NAAASMN1; SMN2HTTLMNACYP2C19 | |
| SCHEMBL16380552 | 0.83 | NAAA (0.69) | NAAASMN1; SMN2HTTLMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788316-B1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |