Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924765 | 0.89 | NAAA (0.58) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL16380604 | 0.88 | NAAA (0.68) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL15028306 | 0.88 | NAAA (0.68) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL13667127 | 0.87 | NAAA (0.56) | NAAASMN1; SMN2HTTCYP2C19EPHX1 | |
| SCHEMBL20924712 | 0.87 | NAAA (0.57) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL16380613 | 0.87 | NAAA (0.69) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL16380552 | 0.87 | NAAA (0.69) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL585907 | 0.86 | NAAA (0.57) | NAAASMN1; SMN2HTTCYP2C19EPHX1 | |
| SCHEMBL16376178 | 0.85 | NAAA (0.64) | NAAASMN1; SMN2HTTCYP2C19METAP1 | |
| SCHEMBL16376171 | 0.85 | NAAA (0.64) | NAAASMN1; SMN2HTTCYP2C19METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1434803-A | Cyclic lactams as inhibitors os A-alpha protein production | BRISTOL MYERS SQUIBB CO (US) | 2003-08-06 | — | — | CN | disclosed |