Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028144 | 0.87 | NAAA (0.40) | NAAAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL16380565 | 0.82 | NAAA (0.49) | NAAAMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20924811 | 0.81 | NAAA (0.36) | NAAASMN1; SMN2 | |
| SCHEMBL16376168 | 0.80 | NAAA (0.47) | NAAALMNAALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL7900619 | 0.77 | NAAA (0.82) | NAAALMNASMN1; SMN2PRKCA | |
| SCHEMBL20924765 | 0.77 | NAAA (0.58) | NAAAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL31634377 | 0.76 | MAPK1 (0.48) | NAAAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL20924712 | 0.76 | NAAA (0.57) | NAAAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL29190226 | 0.75 | NAAA (0.64) | NAAAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL15009586 | 0.75 | NAAA (0.54) | NAAAMAPTMAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788316-B1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |