Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743756 | 0.88 | FFAR4 (0.47) | FFAR4FFAR1CA1ALDH1A1TSHR | |
| SCHEMBL9856778 | 0.88 | FFAR4 (0.47) | FFAR4FFAR1CA1ALDH1A1TSHR | |
| SCHEMBL7744071 | 0.84 | FFAR4 (0.42) | DNM1FFAR4FFAR1CA1ALDH1A1 | |
| SCHEMBL25058850 | 0.80 | DNM1 (0.36) | DNM1FFAR4FFAR1 | |
| SCHEMBL7743695 | 0.80 | FFAR4 (0.42) | FFAR4FFAR1ALDH1A1TSHRACE2 | |
| SCHEMBL27925134 | 0.78 | DNM1 (0.68) | DNM1CA1ALDH1A1TSHRSPHK1 | |
| SCHEMBL23937087 | 0.75 | DNM1 (0.48) | DNM1FFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL25737098 | 0.74 | ALDH1A1 (0.35) | DNM1ALDH1A1TSHR | |
| SCHEMBL16652608 | 0.74 | DNM1 (0.68) | DNM1ALDH1A1TSHRSPHK1 | |
| SCHEMBL14401984 | 0.74 | DNM1 (0.68) | DNM1ALDH1A1TSHRACE2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473611-A1 | TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | Arbutus Biopharma Corporation (CA) | 2019-04-24 | — | — | EP | disclosed |