SCHEMBL20925237

SCHEMBL20925237

CCCc1cnc2c3ccccc3c3cccc(Br)c3n12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
GRM2 Q14416 1/20 0.32
ADK P55263 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17557175 0.86
SCHEMBL17557191 0.78 PDE1A (0.36)
SCHEMBL17557194 0.74
SCHEMBL18477796 0.73
SCHEMBL20367929 0.64 RORA (0.48) GAA
SCHEMBL24061929 0.64 KDM4E (0.40) KDM4E
SCHEMBL17576307 0.63 ALDH1A1 (0.35) ALDH1A1KDM4EHPGD
SCHEMBL840366 0.63 CDK8 (0.33) KDM4E
SCHEMBL13286934 0.63 POLB (0.33) KDM4E
SCHEMBL19595218 0.61 NPC1 (0.37) ALDH1A1GAAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3741768-A1 STABILIZED IMIDAZOPHENANTHRIDINE MATERIALS Universal Display Corporation (US) 2020-11-25 EP disclosed
EP-3473635-A1 STABILIZED IMIDAZOPHENANTHRIDINE MATERIALS Universal Display Corporation (US) 2019-04-24 EP disclosed