Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.55 |
| ▸ | BCR | P11274 | 15/20 | 0.55 |
| ▸ | ADK | P55263 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20925387 | 0.86 | ADORA1 (0.56) | ADK | |
| SCHEMBL20925355 | 0.84 | ADK (0.73) | ABL1BCRADK | |
| SCHEMBL19681258 | 0.84 | ADK (0.73) | ABL1BCRADK | |
| SCHEMBL3397073 | 0.84 | ADK (0.73) | ABL1BCRADK | |
| SCHEMBL16609159 | 0.84 | ADK (0.73) | ABL1BCRADK | |
| SCHEMBL18696212 | 0.84 | ABL1 (0.57) | ABL1BCRADK | |
| SCHEMBL13821121 | 0.84 | ADK (0.73) | ABL1BCRADK | |
| SCHEMBL23982316 | 0.79 | ADK (0.54) | ADK | |
| SCHEMBL29398412 | 0.74 | HIF1A (0.53) | ADK | |
| SCHEMBL20691354 | 0.74 | HIF1A (0.52) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150593-B1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA FARBER CANCER INST INC (US) | 2019-04-24 | — | — | EP | disclosed |