Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20925905 | 1.00 | HSP90AA1 (0.39) | HSP90AA1TRAP1HSP90AB1HSP90B1BIRC5 | |
| SCHEMBL8434095 | 0.75 | HSP90AA1 (0.35) | HSP90AA1TRAP1HSP90AB1HSP90B1BIRC5 | |
| SCHEMBL20925945 | 0.74 | ALDH1A1 (0.39) | ALDH1A1BRD4KDM4EGAACREBBP | |
| SCHEMBL20925930 | 0.73 | MAPK1 (0.39) | ALDH1A1BRD4KDM4EGAAMAPT | |
| SCHEMBL831356 | 0.71 | HSP90AA1 (0.39) | HSP90AA1TRAP1HSP90AB1HSP90B1BIRC5 | |
| SCHEMBL3690934 | 0.70 | BIRC5 (0.36) | HSP90AA1TRAP1HSP90AB1HSP90B1BIRC5 | |
| SCHEMBL13792038 | 0.69 | PRKD3 (0.36) | HSP90AA1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL29896751 | 0.69 | BIRC5 (0.47) | HSP90AA1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL5604900 | 0.69 | BIRC5 (0.47) | HSP90AA1BIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL2187570 | 0.69 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240520-B1 | PRODUCTION OF PROPYLENE-BASED POLYMERS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-04-24 | — | — | EP | disclosed |