Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083351 | 0.80 | MAPK1 (0.38) | MAPK1ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL11089180 | 0.74 | NOTUM (0.36) | ALDH1A1CYP1A2CYP2C19GAANOTUM | |
| SCHEMBL20925905 | 0.73 | HSP90AA1 (0.39) | ALDH1A1MAPTKDM4EGAABRD4 | |
| SCHEMBL20925906 | 0.73 | HSP90AA1 (0.39) | ALDH1A1MAPTKDM4EGAABRD4 | |
| SCHEMBL20925945 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C19KDM4EGAA | |
| SCHEMBL13291987 | 0.71 | HCRTR2 (0.33) | BRD4CREBBPDRD2HTR1A | |
| SCHEMBL30864984 | 0.70 | ACHE (0.46) | BRD4CREBBPDRD2HTR1AHTR2A | |
| SCHEMBL8307788 | 0.68 | DRD2 (0.55) | DRD2HTR1A | |
| SCHEMBL15577015 | 0.68 | ADRA2A (0.46) | BRD4CREBBPDRD2HTR1AHTR2C | |
| SCHEMBL13360866 | 0.68 | BRD4 (0.39) | BRD4CREBBPDRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240520-B1 | PRODUCTION OF PROPYLENE-BASED POLYMERS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-04-24 | — | — | EP | disclosed |