Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176499 | 1.00 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL21166372 | 0.98 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL18737457 | 0.98 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL21166382 | 0.98 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL20216150 | 0.95 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL25469140 | 0.95 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL24486557 | 0.92 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL19069142 | 0.92 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL24690197 | 0.89 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2CNR1CNR2THRA | |
| SCHEMBL21108685 | 0.86 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2CNR1CNR2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828300-B2 | Substituted 2,4-diaminopyrimidines as kinase inhibitors | CELGENE CAR LLC (BM) | 2020-11-10 | — | — | US | disclosed |
| US-20190117650-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828300-B2 | Substituted 2,4-diaminopyrimidines as kinase inhibitors | ABL1, DCK, ERBB2 | ZDHHC20 3551/4885ZDHHC2 3121/4885CNR1 4228/4885 |
| US-20190117650-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | ZDHHC20 958/4885ZDHHC2 905/4885CNR1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.