Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 0.93 |
| ▸ | CES1 | P23141 | 12/20 | 0.93 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzil SCHEMBL27881058 | 0.97 | CES2 (0.88) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL2156589 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL28475956 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL9517636 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL7142843 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL66 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL1002038 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL9799726 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL16390243 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL4957522 | 0.93 | CES2 (1.00) | CES2CES1TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163462-B2 | Photosensitive composition, method for forming pattern, and method for manufacturing semiconductor device | RENESAS ELECTRONICS CORPORATION (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090317742-A1 | Photosensitive composition, method for forming pattern, and method for manufacturing semiconductor device | NEC ELECTRONICS CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |