Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.35 |
| ▸ | CDK9 | P50750 | 5/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19576888 | 0.85 | AXL (0.44) | AXLMETPLAUAURKATTK | |
| SCHEMBL20916365 | 0.82 | AXL (0.36) | AXLMETPLAUAURKATTK | |
| SCHEMBL29782434 | 0.82 | AXL (0.36) | AXLMETPLAUAURKATTK | |
| SCHEMBL19551946 | 0.82 | AXL (0.36) | AXLMETPLAUAURKATTK | |
| SCHEMBL24766681 | 0.78 | PIK3CG (0.39) | AXLMETAURKATTKAURKB | |
| SCHEMBL15074148 | 0.73 | AXL (0.48) | AXLMETPLAUAURKATTK | |
| SCHEMBL24763962 | 0.72 | AXL (0.34) | AXLMETAURKATTKAURKB | |
| SCHEMBL15073979 | 0.72 | AXL (0.47) | AXLMETAURKATTKAURKB | |
| SCHEMBL29882342 | 0.72 | AXL (0.47) | AXLMETAURKATTKAURKB | |
| SCHEMBL20929001 | 0.70 | PIK3CB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844016-B2 | Aromatic sulfonamide derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-11-24 | — | — | US | disclosed |
| US-20190119210-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119210-A1 | AROMATIC SULFONAMIDE DERIVATIVES | ARSA, SULT2A1, TPST2 | AXL 848/4885MET 4374/4885PLAU 4394/4885 |
| US-10844016-B2 | Aromatic sulfonamide derivatives | ARSA, SULT2A1, TPST2 | AXL 848/4885MET 4374/4885PLAU 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.