Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379412 | 0.86 | ALOX5 (0.42) | CHRNA7KMT2ATARDBPALDH1A1CHRM2 | |
| SCHEMBL28682845 | 0.84 | ALOX5 (0.41) | CHRNA7KMT2ATARDBPALDH1A1CHRM2 | |
| SCHEMBL660508 | 0.79 | CHRNA7 (0.45) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 | |
| SCHEMBL6573447 | 0.79 | CHRNA7 (0.45) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 | |
| SCHEMBL7328436 | 0.77 | CHRNA7 (0.37) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 | |
| SCHEMBL7416179 | 0.77 | CHRNA7 (0.41) | CHRNA7ALDH1A1CHRM2CYP2D6CHRM1 | |
| Hydrochloric Acid SCHEMBL7362613 | 0.76 | CHRNA7 (0.35) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 | |
| SCHEMBL7323705 | 0.76 | CHRNA7 (0.35) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 | |
| SCHEMBL7424270 | 0.72 | CHRNA7 (0.44) | CHRNA7ALDH1A1CHRM2CYP2D6CHRM1 | |
| SCHEMBL13617347 | 0.72 | CHRNA7 (0.39) | CHRNA7KMT2AALDH1A1CHRM2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |